SESN3抗体-抗体-抗体-生物在线
SESN3抗体

SESN3抗体

商家询价

产品名称： SESN3抗体

英文名称： SESN3Antibody

产品编号： XY24532-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com
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 SESN3抗体Applications

Tested Applications: ELISA, WB
Specificity Reaction: Human; Other species are not tested.Please decide the specificity by homology
Positive WB detected in HepG2 cells
Recommended dilution WB : 1:200-1:2000
 SESN3抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
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  • 24532-1-AP;HepG2 cellsHepG2 cells were subjected to SDS PAGE followed by western blot with 24532-1-AP( SESN3 Antibody) at dilution of 1:600
Product Information SESN3抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: SESN3 fusion protein ag21380 Full Name: Sestrin 3
Caculated Molecular
Weight:		 492aa,57 kDa Observed Molecular 
Weight:		 57 kDa
GenbankNo BC017296 GeneID: 143686
Symbol SESN3 Synonyms SESN3, SEST3, sestrin 3
Background

Sestrins, including sestrin-1 (PA26), sestrin-2 (Hi95), and sestrin-3, are 48 to 65 kDa cystein sulfinyl reductases and they modulate peroxide signaling and antioxidant defense. These proteins selectively reduce or repair hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. Expression of these proteins is regulated by p53, a tumor suppressor protein. Sestrin 3 was identified as a forkhead box O (FoxO) target gene with antioxidant activity. Recently it was reported that sestrin 3 may play an important role in AKT induced increase in ROS and it might be a promising target in selectively killing cancer cells containing high levels of AKT activity. SESN3抗体

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